Journal of Acupuncture and Meridian Studies
Volume 1, Issue 2 , Pages 121-127 , December 2008

Toxicological Study on MUNOPHIL, Water Extract of Panax ginseng and Hericium erinaceum in Rats

  • Il-Dong Park

      Affiliations

    • East-West Cancer Center, Dunsan Oriental Hospital of Daejeon University, Daejeon, South Korea
    • ,
  • Hwa-Seung Yoo

      Affiliations

    • East-West Cancer Center, Dunsan Oriental Hospital of Daejeon University, Daejeon, South Korea
    • ,
  • Yeon-Weol Lee

      Affiliations

    • East-West Cancer Center, Dunsan Oriental Hospital of Daejeon University, Daejeon, South Korea
    • ,
  • Chang-Gue Son

      Affiliations

    • East-West Cancer Center, Dunsan Oriental Hospital of Daejeon University, Daejeon, South Korea
    • ,
  • Min Kwon

      Affiliations

    • Safety Assessment Center, Korea Testing and Research Institute for Chemical Industry, Korea
    • ,
  • Ha-Jung Sung

      Affiliations

    • Safety Assessment Center, Korea Testing and Research Institute for Chemical Industry, Korea
    • ,
  • Chong-Kwan Cho

      Affiliations

    • East-West Cancer Center, Dunsan Oriental Hospital of Daejeon University, Daejeon, South Korea
    • Corresponding Author InformationCorresponding author. East-West Cancer Center, Dunsan Oriental Hospital of Daejeon University, 1136 Dunsan-dong, Seo-gu, Daejeon, 302–122, South Korea

Received 23 September 2008 ,Accepted 30 October 2008.

References 

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  3. Gong M, An J, Lu HZ, Wu CF, Li YJ, Cheng JQ, et al. Effects of denaturation and amino acid modification on fluorescence spectrum and hemagglutinating activity of Hericium erinaceum lectin . Acta Biochim Biophys Sin (Shanghai) . 2004;36:343–350
  4. Mizuno T , Wasa T , Ito H , Suzuki C , Ukai N . Antitumor-active polysaccharides isolated from the fruiting body of Hericium erinaceum, an edible and medicinal mushroom called yamabushitake or houtou . Biosci Biotechnol Biochem . 1992;56:347–348
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  9. Son CG, Shin JW, Cho JH, Cho CK, Yun CH, Chung W, et al. Macrophage activation and nitric oxide production by water soluble components of Hericium erinaceum . Int Immunopharmacol . 2006;6:1363–1369 Epub 2006 Apr 19.
  10. MH YIM , JW Shin , JY Son , SM Oh , SH Han , JH Cho , et al.   Soluble components of Hericium erinaceum induce NK cell activation via production of interleukin-12 in mice splenocyte . Acta Pharmacol Sin . 2007;28:901–907
  11. Coon JT , Ernst E . Panax ginseng: a systematic review of adverse effects and drug interactions . Drug Saf . 2002;25:323–344
  12. Kitts D , Hu C . Efficacy and safety of ginseng . Public Health Nutr . 2000;3:473–485
  13. Ernst E . The risk-benefit profile of commonly used herbal therapies: Ginkgo, St. John's Wort, ginseng, Echinacea, Saw Palmetto, and Kava . Ann Intern Med . 2002;136:42–53 Review. Erratum in: Ann Intern Med 2003;138:79.
  14. Hess FG , Parent RA , Stevens KR , Cox GE , Becci PJ . Effect of subchronic feeding of ginseng extract G-115 in beagle dogs . Food Chem Toxicol . 1983;21:95–97
  15. Siegel RK . Ginseng abuse syndrome: problems with the panacea . JAMA . 1979;241:1614–1615

PII: S2005-2901(09)60032-7

doi: 10.1016/S2005-2901(09)60032-7

Journal of Acupuncture and Meridian Studies
Volume 1, Issue 2 , Pages 121-127 , December 2008

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