Journal of Acupuncture and Meridian Studies
Volume 2, Issue 2 , Pages 135-146 , June 2009

Effect of Zusanli (ST.36) Electroacupuncture at Two Frequencies on the Bioavailability of 99mTc-Sodium Pertechnetate and on Labeling of Blood Constituents in Rats

  • Vasco Senna-Fernandes

      Affiliations

    • Pós-Graduação de Ciências Médicas (PGCM), Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro, Brazil
    • Departamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcântara Gomes (IBRAG), UERJ, Rio de Janeiro, Brazil
    • Academia Brasileira de Arte e Ciência Oriental/Colégio Brasileiro de Acupuntura (ABACO/CBA), Rio de Janeiro, Brazil
    • Corresponding Author InformationCorresponding author. Pós-Graduação de Ciências Médicas (PGCM) – Universidade do Estado do Rio de Janeiro (UERJ); Av. 28 de setembro, 87, CEP: 20551-030, Rio de Janeiro, RJ, Brazil
    • ,
  • Daisy L França

      Affiliations

    • Pós-Graduação de Ciências Médicas (PGCM), Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro, Brazil
    • Departamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcântara Gomes (IBRAG), UERJ, Rio de Janeiro, Brazil
    • Academia Brasileira de Arte e Ciência Oriental/Colégio Brasileiro de Acupuntura (ABACO/CBA), Rio de Janeiro, Brazil
    • ,
  • Kelly CM Santos

      Affiliations

    • Departamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcântara Gomes (IBRAG), UERJ, Rio de Janeiro, Brazil
    • ,
  • Rafael S Sousa

      Affiliations

    • Departamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcântara Gomes (IBRAG), UERJ, Rio de Janeiro, Brazil
    • ,
  • Dilson Silva

      Affiliations

    • Departamento de Ciências Fisiológicas, UERJ, Rio de Janeiro, Brazil
    • ,
  • Célia M Cortez

      Affiliations

    • Departamento de Ciências Fisiológicas, UERJ, Rio de Janeiro, Brazil
    • ,
  • Mario Bernardo-Filho

      Affiliations

    • Departamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcântara Gomes (IBRAG), UERJ, Rio de Janeiro, Brazil
    • ,
  • Marco AM Guimarães

      Affiliations

    • Departamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcântara Gomes (IBRAG), UERJ, Rio de Janeiro, Brazil

References 

  1. Han JS . Acupuncture and endorphins . Neurosci Lett . 2004;361:258–261
  2. Chen XH , Geller EB , Adler MW . Electrical stimulation at traditional acupuncture sites in periphery produces brain opioidreceptor-mediated antinociception in rats . J Pharmacol Exp Ther . 1996;277:654–660
  3. Cho ZH , Hwang SC , Wong EK , Son YD , Kang CK , Park TS , et al.   Neural substrates, experimental evidences and functional hypothesis of acupuncture mechanisms . Acta Neurol Scand . 2006;113:370–377
  4. Senna-Fernandes V , França D , Moreno SF , Santos-Filho S , Rogers PA , Bernardo-Filho M , et al.   The effect of Zusanli (ST. 36) acupuncture on the bio-availability of sodium pertechnetate in Wistar rats . Acupunct Electrother Res . 2006;31:33–44
  5. Gao W , Huang YX , Chen H , Song DY , Wang QL . Regulatory effects of electro-acupuncture at Zusanli on ir-SP content in rat pituitary gland and peripheral blood and their immunity . World J Gastroenterol . 2000;6:581–584
  6. Chou JW , Chang YH , Chang CS , Chen GH . The effect of different frequency electrical acu-stimulation on gastric myoelectrical activity in healthy subjects . Hepatogastroenterology . 2003;50:582–586
  7. Kim SK , Park JH , Bae SJ , Kim JH , Hwang BG , Min BI , et al.   Effects of electroacupuncture on cold allodynia in a rat model of neuropathic pain: mediation by spinal adrenergic and serotonergic receptors . Exp Neurol . 2005;195:430–436
  8. Tseng CS , Shen WC , Cheng FC , Chen GW , Li TC , Hsieh CL . Dynamic change in energy metabolism by electroacupuncture stimulation in rats . Am J Chin Med . 2005;33:767–778
  9. Tian D , Li X , Niu D , Shi Y , Chang JK , Han J . Electroacupuncture up-regulated arcuate nucleus alpha-MSH expression in the rat of diet-induced obesity . Beijing Da Xue Xue Bao . 2003;35:458–461 [In Chinese]
  10. De Vernejoul P , Albarède P , Darra JC . Nuclear Medicine and Acu puncture Message Transmission . J Nucl Med . 1992;33:409–412
  11. Ye X , Zhang S . The effect of electroacupuncture “zusanli” and “neiguan” points on membrane fluidity of red cells in rabbits . Zhen Ci Yan Jiu . 1992;17:42–44
  12. Medeiros MA , Canteras NA , Suchecki D , et al.   c-Fos expression induced by electroacupuncture at the Zusanli point in rats submitted to repeated immobilization . Braz J Med Biol Res . 2003;36:1673–1684
  13. Capriles PV , Dias AP , Costa TE , Oliveira MB , Faria MV , Moura EG , et al.   Effect of eggplant (Solanum melongena) extract on the in vitro labeling of blood elements with technetium-99m and on the biodistribution of sodium pertechnetate in rats . Cell Mol Biol (Noisy-le-grand) . 2002;48:771–776
  14. Lai M , Wang SM , Zhang WL , Wang Y , Huang SQ , Dong W , et al.   Effects of electroacupuncture on tumor growth and immune function in the Walker-256 model rat . Zhongguo Zhen Jiu . 2008;28:607–609 [In Chinese]
  15. Li YQ , Zhu B , Rong PJ , Ben H , Li YH . Neural mechanism of acupuncture-modulated gastric motility . World J Gastroenterol . 2007;13:709–716
  16. Chen JX , Ma SX . Effects of nitric oxide and noradrenergic function on skin electric resistance of acupoints and meridians . J Altern Complement Med . 2005;11:423–431
  17. Chan AK , Vujnovich A , Bradnam-Roberts L . The effect of acupuncture on alpha-motoneuron excitability . Acupunct Electrother Res . 2004;29:53–72
  18. Kimura A , Sato A . Somatic regulation of autonomic functions in anesthetized animals-neural mechanisms of physical therapy including acupuncture . Jpn J Vet Res . 1997;45:137–145
  19. Sato A . The reflex effects of spinal somatic nerve stimulation on visceral function . J Manipulative Physiol Ther . 1992;15:57–61
  20. Bernardo-Filho M , Santos-Fillho S , Moura EG , Maiworm AE , Orlando MMC , Penas ME , et al.   Drug interaction with radio-pharmaceuticals: a review . Braz Arch Biol Technol . 2005;48:13–27
  21. Kovacs FM , Gotzens V , García A , García F , Mufraggi N , Prandi D , et al.   Experimental study on radioactive pathways of hypodermically injected technetium-99m . J Nucl Med . 1992;33:403–407
  22. Newberg AB , Lariccia PJ , Lee BY , Farrar JT , Lee L , Alavi A . Cerebral blood flow effects of pain and acupuncture: a preliminary single-photon emission computed tomography imaging study . J Neuroimaging . 2005;15:43–49
  23. Sternfeld M , Finkelstein Y , Eliraz A , Hod I . Cell membrane activities and regeneration mechanisms as therapy mediators in moxibustion and acupuncture treatments: theoretical considerations . Med Hypotheses . 1990;31:227–231
  24. Deng Y , Yi S , Lin Y , Yan J , Guo H , Xiang Z , et al.   Influence of needling the foot-yangming points on intracellular Ca2+ concentration in smooth muscles of the gastric antrum in rabbits . J Tradit Chin Med . 2007;27:65–69
  25. Jiang KW , Zhang Y , Shui QX . Possible mechanism of electroacupuncture preconditioning for hypoxia/ischemic brain injury protection effect in neonatal rats . Zhongguo Zhong Xi Yi Jie He Za Zhi . 2003;23:914–917 [In Chinese]
  26. Yu S , Kuang P , Zhang F , Liu J . Anti-inflammatory effects of Tianrong acupoint on blood vessels of dura mater . J Tradit Chin Med . 1995;15:209–213
  27. Early PJ , Soddee DB . Principles and Practice of Nuclear Medicine . 2nd ed. Mosby, Toronto: Mosby; 1995;
  28. Liu ZY , Yao XH . Auricular acupuncture combined with iodine salt for treatment of juvenile endemic goitre . Zhongguo Zhen Jiu . 2005;25:702–704 [In Chinese]
  29. Li GL , Zhou ZX , Li JM . Observation on therapeutic effect of picking therapy on Graves' disease . Zhongguo Zhen Jiu . 2006;26:769–771 [In Chinese]
  30. Dhar HL , Vasanti T . Endogenous depression, thyroid function and acupuncture . Indian J Physiol Pharmacol . 2001;45:125–126
  31. Ishizuki Y , Hirooka Y , Murata Y , Tanigawa S . A case of chronic thyroiditis with transient painful thyroiditis occurring after the administration of lipiodol . Nippon Naibunpi Gakkai Zasshi . 1992;68:1089–1095 [In Japanese]
  32. Otsuka N , Fukunaga M , Morita K , Ono S , Nagai K , Katagiri M , et al.   Iodine-131 uptake in a patient with thyroid cancer and rheumatoid arthritis during acupuncture treatment . Clin Nucl Med . 1990;15:29–31
  33. Khettery J , Effmann E , Grand RJ , Treves S . Effect of pentagastrin, histalog, glucagon, secretin, and perchlorate on the gastric handling of 99mTc pertechnetate in mice . Radiology . 1976;120:629–631
  34. Mou XD , Xie PY , Liu JX , Shuai XW , Li J . Effect of electro-acupuncture at Zusanli acupoint on LESP, plasma gastrin and motilin in rats . World Chin J Digestol . 2005;13:1069–1073
  35. Yi SX , Yang RD , Yan J , Chang XR , Ling YP . Effect of electro-acupuncture at Foot-Yangming Meridian on somatostatin and expression of somatostatin receptor genes in rabbits with gastric ulcer . World J Gastroenterol . 2006;12:1761–1765
  36. Zhao BM , Huang YX , Wang ZH , Zhao NX . Effect of electro-acupuncture on gastric acid secretion and its relationship with gastrin and epidermal growth factor in rats . Shijie Huaren Xiaohua Zazhi . 2000;8:275–278 [In Chinese]
  37. Shen D , Wei D , Liu B , Zhang F . Effects of electroacupuncture on gastrin, mast cell and gastric mucosal barrier in the course of protecting rat stress peptic ulcer . Zhen Ci Yan Jiu . 1995;20:46–49
  38. Ouyang H , Yin J , Wang Z , Pasricha PJ , Chen JD . Electroacu-puncture accelerates gastric emptying in association with changes in vagal activity . Am J Physiol Gastrointest Liver Physiol . 2002;282:390–396
  39. Takahashi T . Acupuncture for functional gastrointestinal disorders . J Gastroenterol . 2006;41:408–417
  40. Tatewaki M , Harris M , Uemura K , Ueno T , Hoshino E , Shiotani A , et al.   Dual effects of acupuncture on gastric motility in conscious rats . J Am Physiol Regul Integr Comp Physiol . 2003;285:862–872
  41. Hahm ET , Lee JJ , Lee WK , Bae HS , Min BI , Cho YW . Electroacu-puncture enhancement of natural killer cell activity suppressed by anterior hypothalamic lesions in rats . Neuroimmunomodulation . 2004;11:268–272
  42. Choi GS , Oha SD , Han JB , Bae HS , Cho YW , Yun YS , et al.   Modulation of natural killer cell activity affected by electroacupuncture through lateral hypothalamic area in rats . Neurosci Lett . 2005;329:1–4
  43. Wang J , Wang YQ , Yu J , Cao XD , Wu GC . Electroacupuncture suppresses surgical trauma stress-induced lymphocyte apoptosis in rats . Neurosci Lett . 2005;383:68–72
  44. Cheng XD , Wu GC , He QZ , Cao XD . Effect of continued electroacupuncture on induction of interleukin-2 production of spleen lymphocytes from the injured rats . Acupunct Electrother Res . 1997;22:1–8
  45. Ben H , Zhu Y . The effect of electro-acupuncture at auricular and body acupoints on the curve changes of the pressure-volume of urinary bladder and the electric activity of pelvic nerves of rats . Zhen Ci Yan Jiu . 1995;20:51–54
  46. Tanaka Y , Koyama Y , Jodo E , Kayama Y , Kawauchi A , Ukimura  , et al.   Effects of acupuncture to the sacral segment on the bladder activity and electroencephalogram . Psychiatry Clin Neurosci . 2002;56:249–250
  47. Huang W , Huang K , Xu Q , Wang Z , Sun Y , Cai H , et al.   Histochemical observation of the effect of electroacupuncture on the livers of rats with endotoxic shock . Zhen Ci Yan Jiu . 1995;20:36–39 [In Chinese]
  48. Shimoju-Kobayashi R , Maruyama H , Yoneda M , Kurosawa M . Responses of hepatic glucose output to electro-acupuncture stimulation of the hindlimb in anaesthetized rats . Auton Neurosci . 2004;115:7–14
  49. Callahan RJ , Rabito AC . Radiolabeling of erythrocytes with technetium-99m: role of band-3 protein in transport of pertechnetate across the cell membrane . J Nucl Med . 1990;31:2004–2010
  50. Li ZR , Shen MH , Peng YJ . Progress in researches on the effect of acupuncture in antagonizing oxygen stress . Chin J Integr Med . 2005;11:156–160
  51. Senna-Fernandes V , França DL , de Souza D , Santos KC , Sousa RS , Manoel CV , et al.   Acupuncture at ‘Zusanli’ (ST.36) and ‘Sanyinjiao’ (SP.6) points on the gastrointestinal tract: a study of the bioavailability of 99mTc-sodium pertechnetate in rats . Evid Based Complement Alternat Med . 2009 Feb 12; [Epub ahead of print]
  52. Dekel N , Sonn J , Barbiro-Michaely E , Ornstein E , Mayevsky A . Effects of anesthesia on brain mitochondrial function, blood flow, ionic and electrical activity monitored in vivo . Adv Exp Med Biol . 2009;645:49–54
  53. Donovan J , Brown P . Euthanasia . Curr Protoc Immunol . 2006; Chapter 1: Unit 1.8.
  54. Valenca SS , Lima EA , Dire GF , Bernardo-Filho M , Porto LC . Sodium pertechnetate (Na99mTcO4) biodistribution in mice exposed to cigarette smoke . BMC Nucl Med . 2005;5:1

PII: S2005-2901(09)60046-7

doi: 10.1016/S2005-2901(09)60046-7

Journal of Acupuncture and Meridian Studies
Volume 2, Issue 2 , Pages 135-146 , June 2009

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