Comparing the Effects of Distilled Rehmannia glutinosa, Wild Ginseng and Astragali Radix Pharmacopuncture With Heart Rate Variability (HRV): A Randomized, Sham-controlled and Double-blind Clinical Trial

Taehan, Yook; Jungsuk, Yu; Hwiyong, Lee; Beomyong, Song; Lakhyung, Kim; Jungdu, Roh; Jinchul, Shin; Sungtaek, Lim

doi:10.1016/S2005-2901(09)60061-3

« Previous Next »Journal of Acupuncture and Meridian Studies
Volume 2, Issue 3 , Pages 239-247, September 2009

Comparing the Effects of Distilled Rehmannia glutinosa, Wild Ginseng and Astragali Radix Pharmacopuncture With Heart Rate Variability (HRV): A Randomized, Sham-controlled and Double-blind Clinical Trial

Yook Taehan
- Department of Acupuncture and Moxibustion, Woosuk University, Jeonju, South Korea
- Corresponding author. Woosuk University Oriental Medicine Hospital, 2-5 Junghwasandong Wansangu, Jeonju City, South Korea
Yu Jungsuk
- Department of Acupuncture and Moxibustion, Woosuk University, Jeonju, South Korea
Lee Hwiyong
- Department of Acupuncture and Moxibustion, Woosuk University, Jeonju, South Korea
Song Beomyong
- Department of Acupuncture and Moxibustion, Woosuk University, Jeonju, South Korea
Kim Lakhyung
- Department of Neuropsychiatry, Woosuk University, Jeonju, South Korea
Roh Jungdu
- Department of Acupuncture and Moxibustion, Woosuk University, Jeonju, South Korea
Shin Jinchul
- Department of Acupuncture and Moxibustion, Woosuk University, Jeonju, South Korea
Lim Sungtaek
- Department of Acupuncture and Moxibustion, Woosuk University, Jeonju, South Korea

Received 19 March 2009; accepted 1 July 2009.

Abstract

This study compared the effects of distilled Rehmannia glutinosa, Wild Ginseng and Astragali Radix pharmacopuncture on the autonomic nervous system and heart rate variability. The purpose of the trial was to observe the influence distilled Astragali Radix, Wild Ginseng and Rehmannia glutinosa pharmacopuncture have on the autonomic nervous system. 120 healthy male volunteers were divided into four groups, which consisted of three experimental groups and a control group. This study was a randomized, placebo-controlled, double-blind clinical trial. Volunteers in experimental groups were underwent pharmacopuncture at GB21 (Kyonjong), and volunteers in the control group were injected with normal saline at GB21 (Kyonjong). Heart rate variability was measured seven times: before and after injection, every 5 minutes for 30 minutes. The result was distilled Rehmannia glutinosa, Wild Ginseng and Astragali Radix pharmacopuncture in healthy adult males tended to activate the autonomic nervous system, particularly the sympathetic nervous system.

Key Words: autonomic nervous system , Astragali Radix , HRV , pharmacopuncture , Rehmannia glutinous , Wild Ginseng